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US 5,317,040 AGranted
Method for the treatment of pertussis with aminoguanidine
AssigneeWashington University
InventorWilliam E. Goldman
Life of this patent
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Abstract
A method for the treatment of pertussis is disclosed which comprises administering a selective inhibitor of inducible nitric oxide synthase, preferably aminoguanidine, to a mammalian host susceptible to pertussis in a small but effective amount for inhibiting the toxic effects of TCT released by Bordetella pertussis.
Claims1
A method for treatment of pertussis which comprises administering to a mammalian host an effective amount of aminoguanidine sufficient to inhibit the toxic effects of TCT released by Bordetella pertussis.
Dependencies are inferred from the claim text.