US 5,317,030 A · Method and compositions for helmintic, arthropod ectoparasitic and acaridal infections with novel agents

Abstract

The present invention relates to methods and compositions for the control and prevention of helmintic, arthropod ectoparasitic and acaridal infections, in warm-blooded animals, such as meat-producing animals, and poultry, by administering to said animals a therapeutically or prophylactically-effective amount of new agents designated LL-F28249.alpha., .beta., .gamma., .delta., .epsilon., .xi., .eta., .theta., .iota., .kappa., .lambda., .mu., .nu. and .omega., or mixtures thereof. The invention also relates to methods for the control of plant nematode infestations and other insecticidal activities. These novel agents are produced via a controlled conditioned microbiological fermentation using Streptomyces cyaneogriseus ssp. noncyanogenus, designated LL-F28249 and having deposit accession number NRRL 15773.

Claims15

Dependent claims

A method for the prevention, treatment or control of insecticidal infections in warm-blooded animals, said method comprising:

orally, parenterally or topically administering to an animal an insecticaidally-effective amount of the fermentation broth or whole mash of microrganism Streptomyces cyaneogriseus noncyanogenus, having deposit accession number NRRL 15773, or a mutant thereof, containing agents designated LL-F28249.alpha., LL-F28249.beta., LL-F28249.gamma., LL-F28249.delta., LL-F28249.epsilon., LL-F28249.zeta., LL-F28249.eta., LL-F28249.theta., LL-F28249.iota., LL-F28249.kappa., LL-F28249.lambda., LL-F28249.mu., LL-F28249.nu., and LL-F28249.omega.;
or the pharmaceutically and pharmacologically-acceptable salts thereof, wherein said agents have characteristic spectra as shown in FIGS. I-LVII of the attached drawings.

Dependencies are inferred from the claim text.

Facts

Application

07/712,777Filed 10 Jun 1991 · continuation

Priority

5 Jun 1984

Granted

31 May 1994

Term ends

Not estimatedThe source records don’t support an estimate.

Classification10 codes

C07H 19/01
Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides ; Anhydro-derivatives…
A01N 63/28
Bacteria; Substances produced thereby or obtained therefrom: streptomyces
C12N 1/205
Bacteria; Culture media therefor: bacterial isolates
C12P 1/06
Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes: by using…

Family

Serial617,649Parent of this continuation-in-part · filed 5 Jun 1984

Serial732,251Parent of this continuation · filed 10 May 1985

US 5,198,464 AParent of this continuation

US 4,869,901 AParent of this continuation-in-part

US 5,317,030 AThis patent

From the US filing history. Foreign family members aren’t listed.

Method and compositions for helmintic, arthropod ectoparasitic and acaridal infections with novel agents

Life of this patent

Method and compositions for helmintic, arthropod ectoparasitic and acaridal infections with novel agents

Life of this patent

Abstract

Claims15