Human growth hormone induced improvement in depressed T4/T8 ratio
AssigneeThe University of Tennessee Research Corporation
InventorKenneth A. Kudsk
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Abstract
A method for stimulating the immune system by treating an individual who has been immunocompromised as a result of severe trauma, including closed head injury and infection, with human growth hormone. This treatment leads to an increase in total lymphocyte number, and in an increase in the T4/T8 ratio. The treatment represents an effective therapy for maintaining or stimulating the immunocompetence of an individual who has been immunocompromised.
Claims27
A method for increasing the T4/T8 ratio in a human with a depressed T4/T8 ratio comprising administering an amount of human growth hormone effective to increase the ratio to a level normal for said human.
A method for increasing the T4/T8 ratio in a human with a depressed T4/T8 ratio comprising administering an amount of human growth hormone effective to increase the ratio to a level normal for said human wherein said depressed T4/T8 ratio results from a physical trauma.
A method for increasing the T4/T8 ratio in a human with a depressed T4/T8 ratio comprising administering an amount of human growth hormone effective to increase the ratio to a level normal for said human wherein said depressed T4/T8 ratio results from an infection.
A method for increasing the T4/T8 ratio in a human with a depressed T4/T8 ratio comprising administering human growth hormone releasing hormone or a fragment thereof to said human in an amount sufficient to cause the release of an amount of human growth hormone effective to increase the ratio to a level normal for said human.
Dependencies are inferred from the claim text.