Booster for therapy of diseases with ultrasound and pharmaceutical liquid composition containing the same
OwnerKatsuro Tachibana, Shunro Tachibanainventors
Life of this patent
Estimating the term…
Abstract
A booster comprising a plenty of microbubbles of a gas in a liquid, e.g. about 4.times.10.sup.7 cells/ml of microbubbles of a gas having a diameter of 0.1 to 100 .mu.m in a 3 to 5% human serum albumin solution, and a pharmaceutical liquid composition comprising the booster as set forth above and a medicament, which are useful for the therapy of various diseases together with exposure of ultrasonic, where the therapeutic effects of the medicament is enhanced by the application of ultrasound in the presence of the booster.
Claims16
A booster for enhancing effects of ultrasound in the therapy of diseases, which comprises:
- a. a medicament and
- b. microbubbles of a gas having a diameter of 0.1 to 100 .mu.m in a liquid.
A pharmaceutical liquid composition for the therapy of diseases with application of ultrasound, which comprises:
- a. microbubbles of a gas having a diameter of 0.1 to 100 .mu.m and
- b. a medicament selected from the group consisting of thrombolytic agents, hormones, antibiotics and antineoplastic agents in a liquid.
A method of dosing subjects with a pharmaceutical preparation by:
- a. applying ultrasound to a pharmaceutical liquid composition and
- b. administering said pharmaceutical liquid composition comprising microbubbles of a gas having a diameter of 0.1 to 100 .mu.m and a medicament in a liquid in the therapy of diseases.
Dependencies are inferred from the claim text.