Loading patent…
AssigneePermeable Technologies, Inc.
InventorsHarry J. Spinelli, Waifong L. Anton, Leonard Seidner, Henry D. Coleman, Mohammed I. Ali, Lester Weintraub, Paul White
Estimating the term…
The present invention relates to novel copolymers and contact lenses made from these copolymers comprising preformed silicone-containing acrylic star polymers, graft copolymers and macromonomers, preparation of these contact lenses and a therapeutic method for treating patients with visual impairment. Described is a composition comprising at least about 10% by weight of a preformed silicone-containing acrylic copolymer and no more than about 90% by weight of a matrix formed from the random polymerization of a mixture of monomers. The mixture of monomers comprises at least one hydrophilic monomer and optionally, monomers selected from the group consisting of silicone acrylates, esters of alpha, beta-unsaturated acids and crosslinking monomers. The preformed silicone-containing acrylic copolymer is preferably copolymerized throughout the matrix. The final compositions are hydrated to a final water content of at least about 10% by weight.
A composition comprising at least about 10% by weight of at least one preformed silicone-containing acrylic copolymer and no more than about 90% by weight of a matrix formed from the polymerization of a mixture of monomers in combination with said preformed acrylic copolymer, said mixture of monomers or said preformed copolymer derived from an amount of hydrophilic monomer effective to provide a final composition which upon hydration comprises at least about 10% by weight water, said preformed acrylic copolymer being dispersed or copolymerized throughout said matrix.
A composition comprising about 10% to about 98% by weight of at least one preformed silicone-containing acrylic copolymer and about 2% to about 90% by weight of a matrix formed from the random polymerization of a mixture of monomers in combination with said preformed acrylic copolymer, said preformed acrylic copolymer comprising at least one hydrophilic block and at least one hydrophobic, permeable block comprising at least about 50% by weight of silicone acrylate units, said mixture of monomers comprising at least one hydrophilic monomer in an amount effective to provide a composition which comprises at least about 10% by weight water after hydration, said preformed silicone-containing acrylic copolymer being copolymerized throughout said matrix.
A contact lens manufactured from a composition comprising about 10% to about 98% by weight of at least one preformed silicone-containing acrylic copolymer and about 2% to about 90% by weight of a matrix formed from the random polymerization of a mixture of monomers in combination with said preformed acrylic copolymer, said preformed acrylic copolymer comprising at least one hydrophilic block and at least one hydrophobic, permeable block, said mixture of monomers comprising at least one hydrophilic monomer in an amount effective to provide a composition which comprises at least about 10% by weight water after hydration, said preformed silicone-containing acrylic copolymer being copolymerized throughout said matrix.
Dependencies are inferred from the claim text.