(S)-(+)-hydroxychloroquine
AssigneeSterling Winthrop Inc.
InventorsVera J. Stecher, William F. Michne
Life of this patent
Estimating the term…
Abstract
(S)-(+)-Hydroxychloroquine substantially free of (R)-(-)-hydroxychloroquine, or a pharmaceutically acceptable acid-addition salt thereof and a method of use thereof and a composition containing it for the treatment of malaria, lupus erythematosus or rheumatoid arthritis.
Claims12
(S)-(+)-2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol substantially free of (R)-(-)-2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol, or a pharmaceutically acceptable acid-addition salt thereof.
A method of treating malaria, lupus erythematosus or rheumatoid arthritis in a human which comprises administering to the human an amount effective to treat malaria, lupus erythematosus or rheumatoid arthritis of (S)-(+)-2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol substantially free of (R)-(-)-2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol, or a pharmaceutically acceptable acid-addition salt thereof.
A composition for treating malaria, lupus erythematosus or rheumatoid arthritis in a human comprising (S)-(+)-2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol substantially free of (R)-(-)-2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol, or a pharmaceutically acceptable acid-addition salt thereof in an amount effective for the treatment of malaria, lupus erythematosus or rheumatoid arthritis and a pharmaceutically acceptable vehicle.
Dependencies are inferred from the claim text.