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US 5,313,162 AGranted
Apparatus for throughflow NMR spectroscopy, especially for cell suspensions
AssigneeForschungszentrum Julich GmbH
InventorsAlbert De Graaf, Ulrich Probst
Life of this patent
Estimating the term…
Abstract
A combined fermenter and measuring tube for NMR throughflow spectroscopy on cell suspensions in which the measurement tube has a capacity of 3 to 20 ml in the measuring zone of the magnet and a fermenter is a premagnetization reservoir of greater cross section of a capacity of at least 100 ml in the repolarization range. A liquid circulator is provided to provide a throughflow rate of 5 to 250 ml/s in the measuring tube.
Claims15
An apparatus for through-flow nuclear magnetic resonance spectroscopy, comprising:
- a wide-bore cryogenic magnet having a vertical bore formed with a large-diameter upper section and a small-diameter lower section, said lower section being formed with a measurement element defining a measuring region;
- a measuring tube formed with a closed bottom and received in said lower section of said vertical bore and having a volumetric capacity in said measuring region of 3 to 20 ml;
- a premagnetization reservoir of a cross section greater than a cross section of said measuring tube and received in said upper section and communicating with said measuring tube at a lower end of said reservoir, said premagnetization reservoir having a volumetric capacity of at least 100 ml over a portion of said reservoir which extends upwardly from said lower end and over zone of the bore in which a magnetic field strength of said magnet is at least 50% of a magnetic field strength in said measuring region;
- and
- means for continuously circulating a liquid carrying a cell suspension between said reservoir and said measuring tube, providing a throughflow in the measuring tube of between 5 and 250 ml/s.
2 more elements
Dependencies are inferred from the claim text.