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US 5,313,007 AGranted
Substituted pentaalkylchromans
AssigneesLonza Ltd., Sankyo Company, Limited
InventorDavid Laffan
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Abstract
The substituted pentaalkylchromans of the general formula: ##STR1## wherein R denotes a lower alkyl group having 1 to 4 C atoms and Hal denotes chlorine, bromine or iodine, are novel intermediates for the preparation of hypolipidaemic pharmaceuticals. A process for their preparation is described in which a trialkylhydroquinone is reacted with a halogenated butenol to give a substituted tetraalkylhydroquinone, which is finally cyclized to the final product.
Claims2
A substituted tetraalkylhydroquinone of the formula:
- ##STR12## wherein R denotes a lower alkyl group having 1 to 4 C atoms and Hal denotes chlorine, bromine or iodine.
2-(1-Chloro-2-methylbut-2-en-4-yl)-1,4-dihydroxy-3,5,6-trimethylbenzene of the formula:
- ##STR13##
Dependencies are inferred from the claim text.