2-amino-7-hydroxytetralin carboxylalkyl ethers
AssigneeElf Sanofi
InventorsUmberto Guzzi, Roberto Cecchi, Luciano Manara
Life of this patent
Estimating the term…
Abstract
The invention relates to 2-amino-7-hydroxytetralin carboxyalkyl ethers of formula ##STR1## wherein Alk represents a straight or branched (C.sub.3 -C.sub.5)alkylene group, and R is hydrogen or (C.sub.1 -C.sub.4)alkyl, useful as starting materials in the synthesis of 7-substituted phenylethanolaminotetralins of formula (XII) ##STR2## wherein X represents hydrogen, halogen, (C.sub.1 -C.sub.4)alkyl, or trifluoromethyl which are useful as spasmolytics and anti-glaucoma agents. The new 7-substituted phenylethanolaminotetralins (XII) as well as the intermediates in the preparation of the compounds (I), the N-protected 2-amino-7-hydroxytetralin carboxyalkyl ethers, are also claimed.
Claims4
A 2-amino-7-hydroxytetralin carboxyalkyl ether of formula (I) ##STR20## wherein Alk represents a straight or branched (C.sub.3 -C.sub.5)-alkylene chain, and R represents hydrogen or (C.sub.1 -C.sub.4)-alkyl or a salt thereof.
Dependencies are inferred from the claim text.