Ocular hypotensive 2-decarboxyl-2-acylthioalkyl prostaglandin derivatives
AssigneeAllergan, Inc.
InventorMing F. Chan
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Abstract
The present invention relates to 2-decarboxyl-2-acylthioalkyl prostaglandins that are potent ocular hypotentives, and are particularly suitable for the management of glaucoma.
Claims4
A pharmaceutical composition for the treatment of ocular hypertension, comprising an amount sufficient to treat ocular hypertension of a compound of formula (III), wherein R is an acyl group derived from an alkylcarboxylic acid having from 1 to 6 carbon atoms in the alkyl moiety, and both R.sub.4 and R.sub.5 are hydrogen. ##STR6##
A method of treating ocular hypertension, which comprises applying to the eye an amount sufficient to treat ocular hypertension of a compound of formula (III), wherein R is an acyl group derived from an alkylcarboxylic acid having from 1 to 6 carbon atoms in the alkyl moiety, and both R.sub.4 and R.sub.5 are hydrogen. ##STR7##
Dependencies are inferred from the claim text.