Indole derivatives

A compound of the formula:

• ##STR18## wherein R.sup.1 is carboxy of pharmaceutically acceptable salts and esters thereof;
• R.sup.2 is hydrogen, lower alkyl or halogen;
• R.sup.3 is phenyl, naphthyl, phenyl or naphthyl each substituted by from one to three C.sub.1-6 alkyl groups, mono- di- or triphenyl(C.sub.1-6)alkyl;
• mono-, di- or triphenyl(C.sub.1-6)alkyl substituted by from one to three substituents selected from the group consisting of C.sub.1-6 alkyl, halogen, cyano, carboxy, mono-, di- or triphenyl(C.sub.1-6)alkyoxycarbonyl, mono- or di(lower)alkylphenylcarbamoyl, di(C.sub.1 -C.sub.6)alkylcarbamoyl, phenylcarbamoyl and (C.sub.1 -C.sub.6)alkylphenylcarbamoyl;
• A is lower alkylene which may be substituted by oxo or lower alkylene,
• Q is carbonyl or lower alkylene,
• X is ##STR19## in which R.sup.4 is hydrogen or C.sub.1-6 alkyl, and
• R.sup.5 is hydrogen, C.sub.1-6 alkyl or Y--Z--R.sup.3,
• Y is a bond or lower alkylene,
• Z is lower alkylene, ##STR20## in which R.sup.6 is hydrogen, (C.sub.1 -C.sub.6) alkyl, mono-, di- or triphenyl(C.sub.1-10)alkyl, C.sub.1-6 alkyl or lower alkoxycarbonyl substituted mono-, di- or triphenyl(C.sub.1-6)alkyl or pharmaceutically acceptable carboxylic acid acyl, and pharmaceutically acceptable salts thereof.