Antibacterial antiplaque oral composition
AssigneeColgate-Palmolive Company
InventorsAbdul Gaffar, Nuran Nabi, John Afflitto, Orum Stringer, Michael Prencipe
Life of this patent
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Abstract
An oral composition dentifrice containing an orally acceptable vehicle, about 30-75% by weight of a dentally acceptable water-insoluble polishing agent, a substantially water-insoluble noncationic antibacterial antiplaque agent, such as 2,4,4'-trichloro-2.sup.1 -hydroxy-diphenyl ether (triclosan) an antibacterial enhancing agent which enhances the delivery of said antibacterial agent to, and retention thereof on, oral surfaces, and a surface active agent and/or a flavoring oil.
Claims12
An oral composition for attaching, adhering or bonding a plaque-inhibiting agent to oral tooth and gum surfaces comprising in an orally acceptable aqueous humectant vehicle, about 30-70% by weight of a dentally acceptable water-insoluble polishing agent, an effective antiplaque amount in the range of about 0.01-5% by weight of a substantially water insoluble noncationic antibacterial agent, at least one of a surface active agent or a flavoring oil and an effective amount in the range of about 0.05-4% by weight of water-soluble or swellable antibacterial-enhancing agent having an average molecular weight of about 100 to about 1,000,000 which contains at least one acid phosphonic delivery-enhancing functional group and at least one organic retention-enhancing group, which delivery-enhancing group enhances attachment, adherence or bonding of antibacterial agent to oral tooth and gum surfaces, wherein said antibacterial-enhancing agent is poly(beta-styrene-phosphonic acid), poly(alpha-styrenephosphonic acid) polymer, or a polymer of either styrenephosphonic acid monomer with the other or with another ethylenically unsaturated polymerizable monomer and said vehicle is other than polyethylene glycol which reduces the antibacterial activity of said antibacterial agent.
An oral dentifrice composition comprising in an orally acceptable aqueous humectant vehicle, about 30-75% by weight of dentally acceptable water insoluble polishing agent, about 0.01-5% of a substantially water insoluble noncationic antibacterial agent, and about 0.05-4% of poly(beta-styrene-phosphonic acid), copoly(beta-styrene-phosphonic acid/vinyl phosphonic acid), or poly(alpha-styrene-phosphonic acid), said composition containing one or both surface active agent and a flavoring oil and said vehicle is other than polyethylene glycol which reduces the antibacterial activity of said polyethylene glycol.
Dependencies are inferred from the claim text.