Leukotriene B.sub.4 antagonists

Abstract

This invention relates to compounds of Formula I and the stereoisomers and pharmaceutically acceptable salts thereof ##STR1## wherein R is alkyl, alkenyl, alkynyl, or cycloalkylalkyl; R.sup.1 is alkyl; R.sup.2 is hydrogen, alkyl; R.sup.6 is alkyl; n is 1 to 5; p is 0 to 6; x is 0 or 2; and R.sup.4 and R.sup.5 are independently hydrogen or alkyl or together with N form a cycloalkylamine. The compounds of Formula I are leukotriene B.sub.4 antagonists and are useful as anti-inflammatory agents and in treating disease conditions mediated by LTB.sub.4.

Dependencies are inferred from the claim text.