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US 5,310,938 AGranted
Substituted arylpyrrole compounds
AssigneeAmerican Cyanamid Company
InventorsDale G. Brown, Robert E. Diehl, Donald P. Wright, Jr., Jack K. Siddens, deceased
Life of this patent
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Abstract
This invention relates to methods and compositions for treating, controlling, preventing and protecting warm-blooded animals from infestation and infection by helminths, acarids and arthropod endo- and ectoparasites by administering or applying to the animals a substituted arylpyrrole compound.
Claims20
A compound having the formula I structure:
- ##STR85## wherein X is F, Cl, Br, I, or CF.sub.3 ;
- Y is F, Cl, Br, I, or CF.sub.3 or CN;
- W is CN or NO.sub.2 ;
- A is H;
- C.sub.1 -C.sub.4 alkyl optionally substituted with from one to three halogen atoms,
- one hydroxy,
- one C.sub.1 -C.sub.4 alkoxy,
- one C.sub.1 -C.sub.4 alkylthio,
- one phenyl optionally substituted with C.sub.1 -C.sub.3 alkyl, C.sub.1 -C.sub.3 alkoxy, or one to three halogen atoms,
- one phenoxy optionally substituted with one to three halogen atoms, or
- one benzyloxy optionally substituted with one halogen substituent;
- C.sub.1 -C.sub.4 carbalkoxymethyl;
- C.sub.3 -C.sub.4 alkenyl optionally substituted with from one to three halogen atoms;
- cyano;
- C.sub.3 -C.sub.4 alkynyl optionally substituted with one halogen atom;
- di-(C.sub.1 -C.sub.4 alkyl) aminocarbonyl;
- or
- C.sub.4 -C.sub.6 cycloalkylaminocarbonyl;
- L is H, F, Cl, or Br;
- M and R are each independently H, C.sub.1 -C.sub.3 alkyl,
- C.sub.1 -C.sub.3 alkoxy, C.sub.1 -C.sub.3 alkylthio, C.sub.1 -C.sub.3 alkylsulfinyl,
- C.sub.1 -C.sub.3 alkylsulfonyl, cyano, F, Cl, Br, I, nitro,
- CF.sub.3, R.sub.1 CF.sub.2 Z, R.sub.2 CO or NR.sub.3 R.sub.4, or when M and R are on adjacent positions and taken with the carbon atoms to which they are attached they may form a ring in which MR represents the structure:
- --OCH.sub.2 O--, --OCF.sub.2 O-- or ##STR86## Z is S(O).sub.n or O;
- R.sub.1 is H, F, CHF.sub.2, CHFCl, or CF.sub.3 ;
- R.sub.2 is C.sub.1 -C.sub.3 alkyl, C.sub.1 -C.sub.3 alkoxy, or NR.sub.3 R.sub.4 ;
- R.sub.3 is H or C.sub.1 -C.sub.3 alkyl;
- R.sub.4 is H, C.sub.1 -C.sub.3 alkyl, or R.sub.5 CO;
- R.sub.5 is H or C.sub.1 -C.sub.3 alkyl;
- and
- n is an integer of 0, 1 or 2.
28 more elements
Dependencies are inferred from the claim text.