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US 5,310,900 AGranted
Streptogramin derivatives and their preparation
AssigneeRhone-Poulenc Rorer S.A.
InventorsJean-Claude Barriere, Marie-Christine Dubroueucq, Maurice Fleury, Martine Largeron, Jean-Marc Paris
Life of this patent
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Abstract
A Streptogramine derivative of formula (I) is disclosed, wherein the symbol Y is a hydrogen atom, a methyl amino or dimethylamino radical, or a protected methylamino radical, and the symbol R represents a methyl or ethyl radical. ##STR1##
Claims5
Process for preparing a streptogramin of formula:
- ##STR6## in which Y is a hydrogen atom or a methylamino or dimethylamino radical or a radical of structure:
- ##STR7## in which R' is an amino-protecting radical and R is a methyl or ethyl radical, comprising the reductive cleavage of a streptogramin of formula:
- ##STR8## in which Y and R are defined as above, is performed in an acid medium, and the product obtained is then optionally converted to an addition salt with an acid.
Dependencies are inferred from the claim text.