Quinolylmethoxyphenyl-acetamides
AssigneeBayer Aktiengesellschaft
InventorsSiegfried Raddatz, Klaus-Helmut Mohrs, Michael Matzke, Romanis Fruchtmann, Armin Hatzelmann, Reiner Muller-Peddinghaus
Life of this patent
Estimating the term…
Loading patent…
AssigneeBayer Aktiengesellschaft
InventorsSiegfried Raddatz, Klaus-Helmut Mohrs, Michael Matzke, Romanis Fruchtmann, Armin Hatzelmann, Reiner Muller-Peddinghaus
Estimating the term…
Quinolylmethoxyphenyl-acetamides of the formula: ##STR1## in which A, B, D, E, G, L and M are hydrogen, hydroxyl, halogen, cyano, carboxyl, nitro, trifluoromethyl, trifluoromethoxy, alkyl, alkoxy or optionally substituted aryl; R.sub.1 represents optionally substituted cycloalkyl; and R.sub.2 and R.sub.3 independently represent hydrogen, alkyl, benzyl, or optionally substituted cycloalkyl; or together represent piperidinyl, morpholino, or piperazinyl; show a high in vitro activity as leukotriene synthesis inhibitors and, therefore, are suitable for the treatment and prevention of inflammations.
Quinolylmethoxyphenyl-acetamide of the formula ##STR54## in which A, B, D, E, G, L and M independently of one another represent hydrogen, hydroxyl, halogen, cyano, carboxyl, nitro, trifluoromethyl, trifluoromethoxy or represent straight-chain or branched alkyl or alkoxy each having up to 8 carbon atoms, or represent aryl having 6 to 10 carbon atoms, which is optionally substituted by halogen, hydroxyl, nitro or cyano,
Dependencies are inferred from the claim text.