Process for producing a hexahydropyridazine-1,2-dicarboxy derivative
AssigneeIhara Chemical Industry Co., Ltd.
InventorTadashi Nakayama
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Abstract
An industrial process which is a process for producing a hexahydropyridazine-1,2-dicarboxy derivative in good yield, is provided. By reacting a hydrazine dicarboxy derivative of the general formula (1): ROC--NH--HN--COR (1) (wherein R is an alkoxy group or an aryl group) with a dihalogenobutane of the general formula (2): X--CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 --X (2) (wherein X is a chlorine or bromine atom) in the presence of a base selected from an alkali metal carbonate or hydroxide, a hexahydropyridazine-1,2-dicarboxy derivative represented by the general formula: ##STR1## (wherein R has the same meaning as R in the above general formula (1)) is obtained efficiently.
Claims2
A process for producing a hexahydropyridazine-1,2-dicarboxy compound represented by the formula:
- ##STR6## (wherein R has the same meaning as R in the following formula (1)), which comprises reacting a hydrazine dicarboxy compound represented by the formula:
- ROC--NH--HN--COR (1)
- (wherein R is an alkoxy group or an aryl group) with a dihalogenobutane represented by the formula:
- X--CH.sub.2 CH.sub.2 CH.sub.2 CH.sub.2 --X (2)
- (wherein X is a chlorine or bromine atom) in the presence of a base selected from an alkali metal carbonate or hydroxide, wherein when R is alkoxy, said base is an alkali metal carbonate.
Dependencies are inferred from the claim text.