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US 5,310,726 AGranted
Lipopeptide compounds
AssigneeMerck & Co., Inc.
InventorJames M. Balkovec
Life of this patent
Estimating the term…
Abstract
Antifungal and antiparasital lipopeptide compounds stable in aqueous media are described. Stability in aqueous media render lipopeptides more useful for compositions for therapeutic applications.
Claims5
A compound having the formula:
- ##STR16## where X is H or OH,
- R is
- (a) a straight or branched chain alkyl from 5 to 23 carbon atoms,
- (b) a straight or branched chain alkenyl from 5 to 23 carbon atoms,
- (c) phenyl and substituted phenyl wherein the substituent is C.sub.1 to C.sub.10 alkyl, C.sub.1 to C.sub.10 alkoxy, C.sub.1 or C.sub.10 alkylamino, or C.sub.1 to C.sub.10 thioalkoxy;
- or
- (d) heteroaryl selected from the group consisting of pyrryl, thiophenyl, furyl, indolyl, benzothiophenyl, benzofuryl, imidazolyl, benzimidazolyl, and pyridinyl.
4 more elements
Dependencies are inferred from the claim text.