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AssigneeKyorin Pharmaceutical Co., Ltd.
InventorsMichiro Ohnota, Kyuya Okamura, Yoshihiro Hirata, Koji Murakami, Mitsuo Ohashi
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The present invention provides novel thiazolidine-2,4-dione derivatives possessing blood sugar-lowering action and aldose reductase-inhibitory action, their salts, their preparation processes and drugs containing them, and relates to thiazolidine-2,4-dione derivatives represented by a general formula (1) ##STR1## [wherein R.sup.1 and R.sup.2 denote identically or differently hydrogen atoms, halogens, lower alkyl groups, hydroxyl groups, lower alkoxy groups, nitro groups or amino groups (said amino group may be substituted with lower alkyl group or lower alkanoyl group, R.sup.3 denotes a hydrogen atom or lower alkyl group, A denotes a lower alkylene or carbonyl group, and B and W denote differently lower alkylenes, carbonyl groups or bonding hands], or their salts.
Thiazolidine-2,4-dione derivatives represented by a general formula (1) ##STR12## wherein R.sup.1 and R.sup.2 each identically represent hydrogen atoms, halogens, lower alkyl groups, hydroxyl groups, lower alkoxy groups, nitro groups or amino groups wherein said amino group may be substituted with lower alkyl group or lower alkanoyl group, R.sup.3 denotes a hydrogen atom or lower alkyl group, A denotes a lower alkylene or carbonyl group, and B and W denote differently lower alkylenes, carbonyl groups or a bond, or their salts.
Dependencies are inferred from the claim text.