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US 5,308,837 AGranted
5'-amine substituted adenosine analogs as immunosuppressants
AssigneeMerrell Dow Pharmaceuticals Inc.
InventorTerry L. Bowlin
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Abstract
The present invention relates to a method of effecting immunosuppression in a patient in need thereof comprising administering to said patient an effective immunosuppressive amount of certain 5'-amine substituted adenosine analogs.
Claims8
A method of effecting immunosuppression in a patient in need thereof comprising administering to said patient an effective immunosuppressive amount of a compound of the formula ##STR8## wherein R represents H, methyl or ethyl and
- Q represents a radical of formulae Ia to If depicted as follows:
- ##STR9## wherein R.sub.1 is H or F,
- n is an integer 1 or 2,
- V.sub.1 is H or methyl,
- V.sub.2 is H or COOH, and
- W, X, Y and Z are each independently H, F, Cl or Br;
- or a pharmaceutically acceptable salt thereof.
4 more elements
Dependencies are inferred from the claim text.