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US 5,308,459 AGranted
Biosynthetic cerebrospinal fluid control and method of use
AssigneeBaxter Diagnostics Inc.
InventorKathryn D. Herring
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Abstract
The present invention relates to a biosynthetic cerebrospinal fluid control and method of use. Additionally, this invention relates to the isolation and purification of stable liquid human prealbumin, a component in the biosynthetic cerebrospinal fluid control.
Claims2
An electrophoretic method to assess human cerebrospinal fluid comprising:
- a) preparing a stable liquid human based cerebrospinal fluid control, wherein the control is made by the process comprising:
- (i) combining a sufficient amount of lactic acid, chloride, glucose, serum, purified prealbumin, and potassium in a buffer to simulate normal human cerebrospinal fluid;
- (ii) gassing said fluid with oxygen to obtain normal electrophoretic patter for human cerebrospinal fluid;
- and
- (iii) filtering said fluids to remove all microbial contaminants;
- b. obtaining an electrophoretic pattern of said control and a sample human cerebrospinal fluid;
- and
- c. comparing the electrophoretic pattern of the control with the electrophoretic pattern of the sample.
5 more elements
Dependencies are inferred from the claim text.