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US 5,300,060 AGranted
Blood bag system for separation and isolation of neocytes and gerocytes
AssigneeMiles Inc.
InventorEdward J. Nelson
Life of this patent
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AssigneeMiles Inc.
InventorEdward J. Nelson
Estimating the term…
A generally flat, elongated edge-sealed polymeric blood bag having a length to width ratio of at least 2 to 1 and one end portion in tapering communication with a connected single tubing which in turn is in closed communication via a Y-connector with both a bag access port and at least one other Y-connector. The second Y-connector is in closed communication with at least one auxiliary bag, preferably two auxiliary bags. Once the upper neocyte portion is expressed from the elongated blood bag the lower, more dense gerocytes can be saved in the original elongated bag or expressed into another connected bag via the Y-connector assembly for subsequent use or storage. The bag system is especially useful for separating and isolating both components of a neocyte/gerocyte red blood cell mixture in an open system and for providing a means for saving the otherwise discarded gerocytes for subsequent use. A physiological solution can be introduced via the Y-connector assemblies into the elongated bag to reconstitute the dense gerocytes.
A method of preparing both neocytes and gerocytes from a blood cell mixture containing some from the group consisting essentially of neocytes, gerocytes, and supernatant including plasma and preservative solution, the method comprising the steps of:
A method of preparing, from an initial mixture of red blood cells and white blood cells including leukocytes, both neocytes and gerocytes from a blood cell mixture containing some from the group consisting essentially of neocytes, gerocytes, and supernatant including plasma and preservative solution, the method comprising the sequential steps of:
A method of preparing, from an initial mixture of red blood cells and white blood cells including leukocytes, both neocytes and gerocytes from a blood cell mixture containing some from the group consisting essentially of neocytes, gerocytes, and supernatant including plasma and preservative solution, the method comprising the sequential steps of:
A method of preparing both neocytes and gerocytes from a blood cell mixture containing some from the group consisting essentially of neocytes, gerocytes, and supernatant including plasma and preservative solution, the method comprising the steps of:
Dependencies are inferred from the claim text.