Assembled viral particles and their use in a vaccine to rotaviral disease
AssigneeUniversity of Saskatchewan
InventorsMark J. Redmond, Mohammed K. Ijaz, Michael D. Parker
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Abstract
Assembled viral particles derived from rotavirus proteins are disclosed. The assembled particles include the inner capsid protein, VP6, in combination with either or both of the outer capsid proteins, VP4 and VP7. These assemblies can be used in vaccine compositions for the treatment and prevention of rotaviral disease.
Claims8
A viral particle assembly capable of eliciting a protective immunological response in a vertebrate subject, said viral particle assembly consisting of:
- (a) an inner capsid protein, VP6;
- and
- (b) outer capsid proteins VP4 and VP7.
A viral particle assembly capable of eliciting an immunological response in a vertebrate subject, said viral particle assembly consisting of VP6 assembled with VP4 and VP7.
Dependencies are inferred from the claim text.