Amide derivatives of Partricin A & Partricin B

A compound of the formula ##STR2## wherein:

• R is the residue of partricin A or partricin B molecule, which is bound to the C-18 carboxyl;
• R.sub.1 is a dimethylamino-substituted cyclohexyl or phenyl group;
• or an alkyl group with 1 to 6 carbon atoms substituted with an N-methyl- or N-ethyl-cycloalkyleneamine with 4 to 5 carbon atoms, with a pyridyl group or with a primary amine group NH.sub.2, a secondary amine group NHR.sub.3 or a tertiary amine group NR.sub.3 R.sub.4, wherein R.sub.3 and R.sub.4 are alkyl groups with 1 to 4 carbon atoms, or NR.sub.3 R.sub.4 together form a basic nitrogen heterocycle, said heterocycle being 5- or 6-membered and optionally containing one or more further heteroatoms chosen from N or O or S;
• R.sub.2 is a hydrogen atom, a methyl group, or has the same meanings as R.sub.1 ;
• or
• NR.sub.1 R.sub.2 together form a basic nitrogen heterocycle, said heterocycle being 5- or 6-membered and optionally containing one or more further N atoms;
• n is an integer of from 0 to 2,
• X is the residue of a pharmacologically and pharmaceutically acceptable organic or inorganic acid.