New sulfated diosmin derivative
AssigneeFabrica Espanola de Productos Quimicos y Farmaceuticos, S.A.
InventorsAurelio Orjales-Venero, Ramon Mosquera-Pestana
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Abstract
The diosmin heptakis (hydrogensulfate) aluminum complex is described, as l as its preparation procedure, characterized by reacting one mole of diosmin with seven moles of a sulfating agent in a dry medium and treatment with an aqueous aluminum hydroxycloride solution of the diosmin heptakis (hydrogensulfate) sodium salt thus obtained. A description of pharmacological assays carried out to confirm the cytoprotective action of the product is included.
Claims7
Diosmin heptakis hydrogensulfate aluminum complex with molecular formula ##STR2## in which R represents SO.sub.3 Al.sub.2 (OH).sub.5.
A method of treating ulcerous lesions comprising administering to a patient in need thereof an effective amount of diosmin heptakis hydrogensulfate aluminum complex.
A pharmaceutical composition which comprises an effective amount of a compound having the formula ##STR3## in which R is SO.sub.3 Al.sub.2 (OH).sub.5 and a pharmaceutically acceptable carrier.
Dependencies are inferred from the claim text.