Back to results
US 5,296,357 AGranted
Method for the detection of plasminogen activators, their inhibitors of stimulators
AssigneeBehringwerke Aktiengesellschaft
InventorHermann Keuper
Life of this patent
Estimating the term…
Abstract
The invention relates to a method for the detection of the functional activity of plasminogen activators and of their inhibitors and stimulators in biological samples, and to reagents for this method.
Claims8
A method for the functional determination of plasminogen activator (PA) activity and the modulation thereof in body fluids, comprising the steps of:
- a) incubating a sample of a biological material with a plasminogen activator substrate in the absence of a methionine oxidizing agent;
- and
- b) determining the resulting plasmin variant by means of a chromogenic plasmin substrate,
- wherein said plasminogen activator substrate is a plasminogen variant with kringle domains 1-4 partially or completely absent.
1 more element
Dependencies are inferred from the claim text.