Dual subcoated simulated capsule-like medicament
AssigneeMcNeil-PPC, Inc.
InventorsMarli F. Batista, Thomas J. Markley
Life of this patent
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Abstract
A simulated capsule-like medicament comprising a dual subcoating comprising an initial subcoating of a water soluble film forming polymer, e.g. povidone and a secondary subcoating of a mixture of two soluble film forming polymers, e.g. povidone and hydroxypropyl methylcellulose and a hydrophobic plasticizer, e.g. castor oil, which provides for a smooth uniform and substantially bubble free outer coating, e.g. gelatin, for the capsule-like medicament; and a process of making such medicaments.
Claims17
A simulated capsule medicament comprising:
- a solid caplet core comprising a medicament;
- a dual subcoating composition on the caplet core comprising an initial subcoating applied to the caplet core comprising povidone and a second subcoating comprising a mixture of povidone, hydroxypropyl comprising and castor oil;
- and a smooth gelatinous outer coating.
A simulated capsule medicament comprising:
- a solid caplet medicament core having a slight convex bowed shape;
- a dual subcoating composition on the caplet core comprising an initial subcoating comprising about 0.1% povidone and a second subcoating comprising about 4% of a mixture of hydroxypropyl methylcellulose and castor oil by weight of the total weight of the subcoated caplet core;
- and a smooth gelatinous outer coating.
A simulated capsule medicament, comprising:
- a solid caplet core comprising a medicament;
- a dual subcoating composition on the caplet core comprising an initial subcoating applied to the caplet core comprising povidone and a second subcoating comprising a mixture of (a) a polymer selected from the group consisting of povidone, hydroxypropyl methylcellulose, and mixtures thereof and (b) castor oil;
- and
- a smooth gelatinous outer coating.
Dependencies are inferred from the claim text.