Diffusion cell with filter screen
AssigneeHanson Research Corporation
InventorsWilliam A. Hanson, Steven W. Shaw
Life of this patent
Estimating the term…
Abstract
A diffusion cell to facilitate the automated removal of test aliquots of liquid from a receptor chamber of the diffusion cell so as to determine percutaneous absorption through a membrane of a donor media from a donor chamber into the receptor chamber of the diffusion cell. There is utilized a sampling port through which the test aliquot is to be removed, the removal being achieved by means of a sample tube. Within the receptor chamber is located a stirring device in the form of a helical coil which is to be rotated to achieve stirring and homogeneous mixing of the liquid within the receptor chamber. Mounted within the coil is a filter screen to prevent particulate matter over a certain size from entering the sample tube and clogging such.
Claims15
A diffusion cell comprising:
- a chamber divided by a membrane into a donor chamber and a receptor chamber, a liquid filling said receptor chamber and being in contact with said membrane, a media supplied into said donor chamber with said media being permitted to diffuse through said membrane and be mixed with said liquid;
- and
- said receptor chamber including a mixing device, said mixing device to be operated to affect eve mixing of said liquid within said receptor chamber, said mixing device comprising a helical coil of a length equal to at least one half the length of said receptor chamber, means for rotating said coil about a longitudinal axis thereof, said helical coil defining an interior surface, a filter screen located within said coil, said filter screen being located directly adjacent said interior surface substantially covering said interior surface, said filter screen forming a basket having an open end spaced from and adjacent to said membrane.
Dependencies are inferred from the claim text.