Process for the preparation of pyridinium intermediates
AssigneeAbbott Laboratories
InventorsXiu C. Wang, Panos Kalaritis, Michelle L. Chang
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Abstract
A process for the preparation of halobenzoic acids, comprising the step of reacting a halonitrobenzene with a pyridinium salt to form an intermediate of the formula ##STR1## wherein R is selected from the group consisting of hydrogen, alkyl, aryl, alkenyl, alkynyl, --CN, --COOR' and --COR' where R' is alkyl or aryl; X is chloro or fluoro; Y is hydrogen, chloro or fluoro; and Z is chloro, bromo or iodo.
Claims11
A process for the preparation of pyridinium intermediates comprising the step of reacting a halonitrobenzene of the formula ##STR10## with a pyridinium salt of the formula ##STR11## to form a pyridinium intermediate of the formula ##STR12## wherein R is selected from the group consisting of hydrogen, C.sub.1 -to-C.sub.10 alkyl, C.sub.2 -to-C.sub.10 alkenyl, C.sub.2 -to-C.sub.10 alkynyl, phenyl, naphthyl, --CN, --COOR', and --COR' where R' is C.sub.1 -to-C.sub.10 alkyl, phenyl or naphthyl;
- X is chloro or fluoro;
- Y is hydrogen, chloro or fluoro;
- and Z is chloro, bromo or iodo.
Dependencies are inferred from the claim text.