Dry eye treatment process and solution
AssigneeOcular Research of Boston, Inc.
InventorsThomas Glonek, Jack V. Greiner, Donald R. Korb
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Abstract
A method and composition for reducing evaporation of an aqueous layer from the surface of the eye. The method comprises applying an admixture of a charged phospholipid and a non-polar oil over the eye, preferably in the form of a meta-stable oil in water emulsion in a dosage not exceeding 100 microliters.
Claims46
An artificial tear film over the aqueous layer of the eye comprising a complex phospholipid having a net charge over said aqueous layer and a layer of an essentially non-polar oil over said layers, said oil layer being present in an amount sufficient to form a tear film over the ocular surface and in a volume that does not exceed about 25 microliters.
A method for reducing evaporation from an aqueous tear film over the surface of an eye, said method comprising applying an essentially non-polar, liquid oil over a film of a charged phospholipid overlying said tear film, said non-polar oil being added in an amount sufficient to form a tear film over the ocular surface an in a volume that does not exceed 25 microliters.
A treatment composition for topical application to the eye, said composition comprising an aqueous oil in water emulsion of an essentially non-polar oil and a charged phospholipid, said emulsion containing said complex phospholipid and said non-polar oil in an amount sufficient to form a tear film over the ocular surface and in a concentration whereby 1 standard 50 microliter drop of said emulsion will contain from about 1 to 25 microliters of said non-polar oil.
Dependencies are inferred from the claim text.