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AssigneeHitachi, Ltd.
InventorsMasako Mizuno, Kenji Tochigi, Yutaka Misawa, Hiroyuki Miyagi, Yoshio Watanabe, Taro Nogami, Junkichi Miura, Yoshinori Takata
Estimating the term…
Stable hemoglobin A.sub.lc (s-A.sub.lc) can be separated from other hemoglobin components and quantitated in a short time by means of a liquid-chromatographic apparatus comprising a separation column packed with a packing material consisting essentially of a porous substance having a carboxyalkyl group combined thereinto, as ion exchanger, a means for injecting a sample into the separation column, a means for passing one or more eluents through the separation column, and a means for detecting hemoglobin, hemoglobin derivatives or glycosylated hemoglobin, the average particle size of the packing material in dry state being 4 .mu.m or less.
An apparatus for liquid chromatography for measuring hemoglobin, hemoglobins derivatives or glycosylated hemoglobin in blood, which comprises:
A system for liquid chromatography for determining hemoglobin, hemoglobin derivatives or glycosylated hemoglobin in blood, which comprises:
An apparatus for liquid chromatography for fractionating hemoglobin into a plurality of fractions by flowing stepwise two or more eluents into a separation column, comprising a separation column, means for calculating proportions of components separated by said separation column, processing means for processing data from the calculation means and means for varying the mixing ratio, switching times or flow rate of two or more eluents on the basis of signals from the processing means to enable the determination of the proportion of A.sub.lc components and the determination of the proportions of labile-A.sub.lc and stable-A.sub.lc in the same said separation column by using the same said two or more eluents.
Dependencies are inferred from the claim text.