Myoinositol derivatives and preparation process thereof
AssigneeMitsui Toatsu Chemicals, Inc.
InventorsShoichiro Ozaki, Yutaka Watanabe, Akira Awaya, Yusaku Ishizuka
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Abstract
Disclosed herein are phosphoric acid esters of myoinositol, which are represented by the following general formula (I): ##STR1## and their salts, as well as a preparation process thereof. The myoinositol derivatives can each be obtained by causing a phosphorylating agent to act on a myoinositol derivative substituted with catalytic reduction removable substituent groups at the positions other than those desired to be substituted by phosphoric acid residual groups and then catalytically reducing the thus-phosphorylated myoinositol.
Claims3
A process for the preparation of 1,4,5-triphospho-myoinositol labelled with tritium or deuterium at the 2-position which comprises reacting a 2-oxo-3,6-di-(catalytic reduction removable group-substituted)-4,5-bis(di-phospho-substituted)-myoinositol with a hydride reducing agent containing a tritium or deuterium labelling atom.
Dependencies are inferred from the claim text.