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US 5,292,901 AGranted
Benzodioxole derivatives
AssigneeEisai Co., Ltd.
InventorsYoshitake Ogata, Makoto Ikeda, Seiichiro Nomoto, Makoto Okita, Naoyuki Shimomura, Toshihiko Kaneko, Takashi Yamanaka, Ieharu Hishinuma, Junichi Nagakawa, Kazuo Hirota, Kaname Miyamoto, Toru Horie, Tsuneo Wakabayashi
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Abstract
A new benzodioxole derivative has a substituent in the phenyl ring which is a carboxyalkylthioalkyl or the like and is effective to treat a liver disease.
Claims8
A benzodioxole derivative having the formula (I) or a pharmaceutically acceptable salt thereof ##STR363## wherein R.sup.3 is H, lower alkyl, or phenethyl;
- and W is (b) ##STR364## wherein R.sup.7 and R.sup.8 are the same or different and selected from H, lower alkyl, benzyl or phenethyl, Y is COOH or CONR.sup.5 R.sup.6, wherein R.sup.5 and R.sup.6 are the same or different and selected from H, lower alkyl and carboxymethyl, or (c) ##STR365## wherein R.sup.7 and R.sup.8 are the same or different and selected from H, lower alkyl, benzyl, or phenethyl, Y is CONR.sup.5 R.sup.6 wherein R5 and R.sup.6 are the same or different and selected from H, lower alkyl, or carboxymethyl.
Dependencies are inferred from the claim text.