5,7-dihydroxy-2-methyl-8-(4-(3-hydroxy-1-(1-propyl))pip eridinyl)-4H-1-benzopyran-4-one, its preparation and its use
AssigneeHoechst Aktiengesellschaft
InventorsRamachandra G. Naik, Shrikant V. Rao, Aftab D. Lakdawala, Mandakini V. Shirole, Bansi Lal, Noel J. de Souza, Jurgen Blumbach
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Abstract
The present invention relates to 5,7-Dihydroxy-2-methyl-8-[4-(3-hydroxy-1-(1-propyl))piperidinyl]-4H-1-benz opyran-4-one its preparation and its use. 5,7-Dihydroxy-2-methyl-8-[4-(3-hydroxy-1-(1-propyl))piperidinyl]-4H-1-benzo pyran-4-one is useful for the treatment of arthritis and/or rheumatism and for the treatment of chronic inflammatory diseases.
Claims6
5,7-Di hydroxy-2-methyl-8-[4-(3hydroxy-1-(1-propyl)piperidinyl]-4H-1-benzopyran-4- one, a compound of formula I ##STR6## the stereoisomers and the pharmacologically tolerable acid addition salts thereof.
Cis-(+ )-5,7-Dihydroxy-2-methyl-8-[4-(3-hydroxy-1-(1-propyl)piperidinyl]-4H-1-benz opyran-4-one and its hydrochloride,
- cis-(-)-5,7-Dihydroxy-2-methyl-8-[4-(3-hydroxy-1-(1-propyl)piperidinyl]-4H- 1-benzopyran-4-one and its hydrochloride and
- cis-(.+-.)-5,7-Dihydroxy-2-methyl-8-[4-(3-hydroxy-1-(1-propyl)piperidinyl]- 4H-1-benzopyran-4-one and its hydrochloride.
Dependencies are inferred from the claim text.