Use of 4-(3-trifluoromethylphenyl)-1,2,3,6-tetrahydropyridine derivatives as free radical scavengers
AssigneeElf Sanofi
InventorsMichel Heaulme, Umberto Guzzi
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Abstract
The invention concerns the use of a compound of formula (I) ##STR1## wherein R and R.sub.1, each independently, represent a hydrogen atom or a methyl group, and its pharmaceutically acceptable acid addition salts, as free radical scavengers. The pharmaceutical compositions containing these compounds may be employed in the treatment and/or prevention of pathological processes involving cell damage due to the formation of free radicals. The invention also concerns the compounds of formula (I) wherein at least one of R and R.sub.1 is methyl, which are new compounds, as well as the process for the preparation thereof and the pharmaceutical compositions containing them.
Claims1
A method of scavenging free radicals in human and animal subjects comprising administering to said subjects an effective amount of a compound of formula (I) ##STR9## wherein R and R.sub.1, each independently, represent a hydrogen atom or a methyl group, or of a pharmaceutically acceptable acid addition salt thereof.
Dependencies are inferred from the claim text.