Morpholinoalkylindenes as antiglaucoma agents

A method for the treatment of glaucoma which comprises administering to a patient in need of such treatment a medicament containing an effective intraocular pressure reducing amount of a compound having the formula:

• ##STR12## wherein Alk is lower-alkylene;
• R.sub.1 is hydrogen, lower-alkyl, Ar or ArCOO;
• R.sub.2 is hydrogen or lower-alkyl;
• R.sub.3 and R.sub.4 are the same or different hydrogen, fluoro, chloro, bromo, hydroxy, lower-alkoxy, lower-alkyl, or trifluoromethyl;
• Ar is phenyl, naphthyl, anthryl, 2-phenylethenyl or a 5- or 6-membered monocyclic or 9- or 10-membered bicyclic fused aromatic heterocyclic ring containing carbon and one or two heteroatoms independently selected from oxygen, nitrogen and sulfur, or such carbocyclic or heterocyclic rings substituted with from 1 to about 3 of lower-alkoxy, lower-alkyl, lower-alkylthio, lower-alkyl sulfinyl, lower-alkyl sulfonyl, hydroxy, cyano, amino, lower-alkylamino, dilower-alkylamino or halo;
• or phamaceutically acceptable acid addition salts thereof.