Sustained release composition and method utilizing xanthan gum and an active ingredient

A method of producing a sustained release composition for slow delivery of a drug as an active ingredient to the gastro-intestinal tract consisting of mixing an effective amount of said active ingredient with xanthan gum and a lubricant, said active ingredient being present in an amount of 40-80 weight percent of said unit dose, said xanthan gum being present in an amount of 20-50 weight percent of the mixture, compacting the mixture and forming the mixture into a unit dose.

A sustained release composition for slow delivery of niacin as an active ingredient to the gastro-intestinal tract consisting of an effective amount of niacin in mixture with xanthan gum and a lubricant, the mixture being in the form of a compacted unit dose, said niacin being present in an amount of 40-80 weight percent of said unit dose, said xanthan gum being present in an amount of 20-50 weight percent of said unit dose.

A method of producing a sustained release composition for slow delivery of niacin as an active ingredient to the gastro-intestinal tract consisting of mixing an effective amount of niacin with xanthan gum and a lubricant, said niacin being present in an amount of 40-80 weight percent of said unit dose, said xanthan gum being present in an amount of 20-50 weight percent of the mixture, compacting the mixture and forming the mixture into a unit dose.

A sustained release composition for slow delivery of a drug as an active ingredient to the gastro-intestinal tract consisting of an effective amount of said active ingredient in mixture with xanthan gum, the mixture being in the form of a unit dose in capsule or tablet form, said active ingredient being present in an amount of 40-80 weight percent of said unit dose, said xanthan gum being present in an amount of 20-50 weight percent of said unit dose.

A method of producing a sustained release composition for slow delivery of a drug as an active ingredient to the gastro-intestinal tract consisting of mixing an effective amount of said active ingredient with xanthan gum, said active ingredient being present in an amount of 40-80 weight percent of said mixture, said xanthan gum being present in an amount of 20-50 weight percent of said mixture, compacting the mixture and forming the mixture into a unit dose in capsule or tablet form.

A sustained release composition for slow delivery of a drug as an active ingredient to the gastro-intestinal tract consisting of an effective amount of said active ingredient, xanthan gum and a lubricant, the mixture being in the form of a unit dose in capsule or tablet form, said active ingredient being present in an amount of 40-80 weight percent of said unit dose and said xanthan gum being present in an amount of 20-50 weight percent of said unit dose.

A method for producing a sustained release composition for slow delivery of a drug as an active ingredient to the gastro-intestinal tract consisting of mixing an effective amount of said active ingredient, xanthan gum and a lubricant, said active ingredient being present in an amount of 40-80 weight percent of said mixture and said xanthan gum being present in an amount of 20-50 weight percent of said mixture, compacting the mixture and forming the mixture into a unit dose in capsule or tablet form.

A sustained release composition for slow delivery of a drug as an active ingredient to the gastro-intestinal tract consisting of an effective amount of said active ingredient, a water soluble carbohydrate-based agglomerate, xanthan gum, and a lubricant, the mixture being in the form of a unit dose in capsule or tablet form, said active ingredient being present in an amount of 40-80 weight percent of said unit dose and said xanthan gum being present in an amount of 20-50 weight percent of said unit dose.