Blood platelet loaded with diagnostic or therapeutic-containing liposome or reconstituted Sendai virus

Abstract

The invention provides loaded platelets that include an absorbed loading vehicle having associated diagnostic or therapeutic agents. A method of loading platelets with diagnostic or therapeutic agents is provided. The method includes combining a loading vehicle having associated diagnostics or therapeutic agents with platelets at sufficient concentration and temperature to allow uptake of the loading vehicle by the platelets. Also provided is a method of targeting diagnostic or therapeutic agents to platelet localizing areas. The method includes the steps of: (a) combining a loading vehicle having associated diagnostic or therapeutic agents with platelets at sufficient concentration and temperature to allow uptake of the loading vehicle by the platelets; (b) isolating the platelets from excess loading vehicle; and (c) administering the isolated platelets to an animal in an effective concentration so as to promote targeting of the isolated platelets to platelet localizing areas. A method of imaging is also provided.

Dependencies are inferred from the claim text.