Process for producing a pharmaceutical tablet using a homozygous white starch
AssigneeAmerican Maize Technology, Inc.
InventorsDavid J. Mauro, Frances L. Turnak
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Abstract
The use of a starch obtained from a plant source that is homozygous in a white recessive gene, such as white common corn starch, has superior compression and ejection forces compared to commercial disintegrantants/binders. The starch derived from common corn containing the homozygous white recessive gene was also found to have comparable whiteness to commercial bleached corn starches used in tableting.
Claims6
In a process for making pharmaceutical tablets wherein compression is used to form the pharmaceutical tablets and wherein starch is used as a binder in formulating the tablets, the improvement which comprises using an effective amount of a white corn starch obtained from a starch bearing plant which is homozygous with the white gene (ww) as a binder in formulating the tablets thereby reducing the amount of energy necessary to eject the tablets compared to bleached common corn starch and microcellulose, the amount of said starch being effective to make the tablets friable.
Dependencies are inferred from the claim text.