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AssigneeThe United States of America as represented by the Secretary of the Navy
InventorAlok Singh
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Novel diacetylenic phospholipids having the diacetylenic moieties chemically decoupled from the rest of the acyl chains by the inclusion of one or more heteroatom, preferably oxygen, spacers on the acyl chains have the chemical formula: ##STR1## where m is 7, 8, 9, 10, 11, 12, or 13, where n is 8, 9, 10, 11, 12, or 13, where W is --O(CO)-- or --OCH.sub.2 --, where X is --CH.sub.2 --, --OCH.sub.2 --, --SCH.sub.2 --, --NHCH.sub.2 --, or --SiMe.sub.2 CH.sub.2 --, where Y is --CH.sub.2 --, --CH.sub.2 O--, --CH.sub.2 S--, --CH.sub.2 NH--, or --CH.sub.2 SiMe.sub.2 --, where Z is --N(CH.sub.3).sub.3, saccharide, or --ROH where R is --(CH.sub.2).sub.p -- and p is 0, 1, 2 or 3, and where X and Y are not both --CH.sub.2 --. Novel tubules made from these diacetylenic phospholipids have high flexibility and variable morphology.
A lipid with the chemical formula ##STR3## wherein m is 7, 8, 9, 10, 11, 12, or 13, wherein n is 8, 9, 10, 11, 12, or 13, wherein W is --O(CO)-- or --OCH.sub.2 --, wherein X is --CH.sub.2 --, --OCH.sub.2 --, --SCH.sub.2 --, --NHCH.sub.2 --, or --SiMe.sub.2 CH.sub.2 --, wherein Y is --CH.sub.2 --, --CH.sub.2 O--, --CH.sub.2 S--, --CH.sub.2 NH--, or --CH.sub.2 SiMe.sub.2 --, wherein Z is --N(CH.sub.3).sub.3, saccharide, or --ROH wherein R is --(CH.sub.2).sub.p -- and p is 0, 1, 2 or 3, and wherein X and Y are not both --CH.sub.2 --.
A composition of lipid tubules, made by the process of:
Dependencies are inferred from the claim text.