Intermediates useful in preparing propenone oxime ethers
AssigneeElf Sanofi
InventorsChristian Congy, Patrick Gueule, Bernard Labeeuw, Murielle Rinaldi
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AssigneeElf Sanofi
InventorsChristian Congy, Patrick Gueule, Bernard Labeeuw, Murielle Rinaldi
Estimating the term…
The invention relates to new propenone oxime ethers, a method of preparing them and pharmaceutical compositions containing them. Said new propenone oxime ethers have the formula ##STR1## in which Ar and Ar' each independently denotes a phenyl group non-substituted, mono or polysubstituted, a 9-anthryl group or a naphthyl group, a pyridyl, thienyl or furyl group; R.sub.1 and R.sub.2 each independently denotes hydrogen, a C.sub.1 -C.sub.4 alkyl group or together with the N-atom to which they are bonded a 1-pyrrolidinyl, piperidino, morpholino or 1-piperazinyl group; M=H, Cl, Br or a C.sub.1 -C.sub.6 alkyl group n=2 or 3. The invention also deals with the salts of compounds of formula (I). Said compounds have good activity in the anti platelet-clotting tests and are also antagonists of the 5HT.sub.2 receptors.
An intermediate compound useful in preparing propenone oxime ethers, said intermediate compound having the formula:
Dependencies are inferred from the claim text.