US 5,290,937 AGranted

Radiolabeling of proteins using alkoxyphenol derivatives

AssigneeE. R. Squibb & Sons, Inc.

InventorFrank P. Tomasella

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Abstract

Novel compounds, useful as radiolabeling reagents, including an alkoxy group on the phenyl ring and having the formula ##STR1## wherein X is a radionuclide are disclosed. The invention further includes novel radiohalogenated proteins as well as processes for preparing such reagents and radiohalogenated proteins.

Claims5

Dependent claims

A compound of the formula ##STR11## wherein X is a radionuclide,

R is ##STR12## n=0 or 1 to 8.

Dependencies are inferred from the claim text.

Facts

Application: 07/975,455Filed 12 Nov 1992
Granted: 1 Mar 1994
Term ends: Not estimatedThe source records don’t support an estimate.

Classification9 codes

A61K 51/1093
Antibodies or immunoglobulins; Fragments thereof , the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised…
C07B 59/001
Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se: acyclic or carbocyclic compounds
C07B 59/002
Introduction of isotopes of elements into organic compounds ; Labelled organic compounds per se: heterocyclic compounds
C07C 69/92
Of monocyclic hydroxy carboxylic acids, the hydroxy groups and the carboxyl groups of which are bound to carbon atoms of a six-membered aromatic…

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