Euthanasia compositions
AssigneeBoard of Trustees operating Michigan State University
InventorsDonald C. Sawyer, Marlee A. Langham, Theodore M. Brody
Life of this patent
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Abstract
An euthanasia solution based upon gamma-hydroxybutramide, a cardiotoxic amount of a compound selected from a chloroquine and quinacrine compound and lidocaine as a base or as a water soluble salt is described. The composition provides effective euthanasia without unwanted side effects, particularly in dogs, cats and horses. In addition, it does not contain substances controlled by the Federal Drug Control Administration.
Claims29
A method for providing euthanasia in a mammal in need thereof which comprises:
- (a) premedicating by intravenous administration to tranquilize the mammal with a tranquilizer immediately prior to euthanasia;
- and
- (b) introducing by injection into the mammal an aqueous euthanasia solution comprising an effective amount for producing euthanasia of a cardiotoxic compound selected from the group consisting of a quinacrine compound and a chloroquine compound and a water solubilized gamma-hydroxybutramide in an anesthetic amount, wherein euthanasia occurs in the mammal.
A method for providing euthanasia in a mammal in need thereof which comprises introducing by injection into the mammal an aqueous solution comprising in admixture an effective amount for producing euthanasia of a cardiotoxic compound selected from the group consisting of a quinacrine compound and a chloroquine compound, a lidocaine selected from the group consisting of a water-solubilized lidocaine as a base and water soluble salts thereof in a cardiotoxic amount, and a water solubilized gamma-hydroxybutramide in an anesthetic amount, wherein euthanasia occurs in the mammal.
A method for providing euthanasia in a mammal in need thereof which comprises:
- introducing by injection into the mammal an effective amount for producing euthanasia of a mixture of gamma-hydroxybutramide dissolved in a water miscible liquid solubilizing agent;
- a chloroquine compound;
- a lidocaine compound;
- and optionally
- a water soluble inorganic salt in an aqueous solution so that the mammal is euthanatized within five (5) minutes.
A composition for providing euthanasia in a mammal which comprises in admixture in an injectable aqueous solution:
- (a) a cardiotoxic compound selected from the group consisting of a quinacrine compound and a chloroquine compound;
- (b) a lidocaine selected from the group consisting of a water solubilized lidocaine as a base and water soluble salts thereof;
- (c) gamma-hydroxybutramide, wherein the solution contains a ratio of gamma-hydroxybutramide to chloroquine or quinacrine of between about 3 to 1 and 6 to 1 and a ratio of lidocaine to gamma-hydroxybutramide of between about 0.01 and 0.15 to 1 in an amount sufficient to produce euthanasia;
- and
- (d) an injectable carrier.
A composition for providing euthanasia in a mammal which comprises in admixture an aqueous solution:
- (a) gamma-hydroxybutramide dissolved in a water immiscible liquid solubilizing agent;
- (b) a water soluble chloroquine compound;
- (c) a lidocaine compound;
- and
- (d) a water soluble potassium salt, wherein the solution contains a ratio of gamma-hydroxybutramide to chloroquine salt of between about 3 to 1 and 6to 1;
- a ratio of gamma-hydroxybutramide to potassium salt of between about 0.01 and 0.02 and a ratio of lidocaine compound to gamma-hydroxybutramide between about 0.01 and 0.015 to 1 and wherein the solution produces euthanasia;
- and
- (e) an injectable carrier.
Dependencies are inferred from the claim text.