Method and device for delivering a bioactive agent
AssigneeDow Corning Corporation
InventorRandall P. Sweet
Life of this patent
Estimating the term…
Abstract
Hot-melt silicone pressure sensitive adhesive composition, methods of using the composition, article made using the composition, and methods of making articles using the composition. The hot-melt silicone pressure sensitive adhesive composition includes a mixture of (i) a silicone resin, (ii) a silicone fluid, and (iii) from about 0.5 to about 10 weight percent, based on the total weight of the silicone resin and the silicone fluid, of a non-flammable hydrocarbon having a weight-average molecular weight of from about 300 to about 1500 as measured by gel permeation chromatography calibrated with narrow distribution polydimethylsiloxane standards.
Claims1
A device for delivering a bioactive agent to a bioactive-agent accepting substrate, comprising:
- (a) a reservoir,
- (b) a bioactive agent contained within the reservoir, and
- (c) a hot-melt silicone pressure sensitive adhesive composition on the reservoir for providing a means for adhering the reservoir to the bioactive-agent accepting substrate, said composition comprising a mixture of
- (i) a trimethylsilyl-endblocked benzene-soluble resinous copolymer containing silicon-bonded hydroxyl radicals and consisting essentially of triorganosiloxy units of the formula R.sub.3 SiO.sub.1/2 and tetrafunctional siloxy units of the formula SiO.sub.4/2 in a ratio of about 0.6 to 0.9 triorganosiloxy units for each tetrafunctional siloxy unit present in the copolymer, wherein R is a monovalent organic radical independently selected from the group consisting of hydrocarbon radicals of from 1 to 6 inclusive carbon atoms, and
- (ii) a silanol-endstopped polydimethylsiloxane fluid, which mixture exhibits tackiness and adhesiveness, said mixture being blended with
- (iii) from about 0.5 to about 10 weight percent, based on the total weight of said resinous copolymer and said polydimethylsiloxane fluid, of a hydrocarbon having a flashpoint equal to or above 100 F. and having a weight-average molecular weight of from about 300 to about 1500 as measured by gel permeation chromatography calibrated with narrow distribution polydimethylsiloxane standards.
Dependencies are inferred from the claim text.