Method for combining a mixture of heterogeneous substances with liposomes
AssigneeLaboratoire Des Stallergenes
InventorsIsabelle Millet-Genin, Francis Puisieux, Tran X. Thao, Liliane Roblot-Treupel
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AssigneeLaboratoire Des Stallergenes
InventorsIsabelle Millet-Genin, Francis Puisieux, Tran X. Thao, Liliane Roblot-Treupel
Estimating the term…
In the method for combining with liposomes heterogeneous substances contained in a mixture, in particular, allergenic substances such as allergens and/or allergenic extracts, contained in an allergenic preparation, by adsorption on the surface of, and/or incorporation in, liposomes which comprise cholesterol, a phospholipid and/or at least one ionic lipid which gives the liposome a positive or negative charge, the liposome or its constituents are combined with the mixture of heterogeneous substances, the pH of the entire combination being higher or lower than the isoelectric point ip of the substances contained in the mixture, depending on whether the ionic lipid is charged positively or negatively respectively.
A method of combining protidic allergens and/or allergenic extracts selected from the group consisting of natural allergens from animal or vegetable origin, allergenic proteins and peptides, with a negatively or positively charged liposome comprised of cholesterol, a phospholipid and/or at least one ionic lipid which gives the liposome a positive or negative charge, comprising
Dependencies are inferred from the claim text.