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US 5,288,895 AGranted
Process for the preparation of a biphenyl derivative
AssigneeElf Sanofi
InventorsMichel Bouisset, Alain Boudin
Life of this patent
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Abstract
The subject of the invention is a process for the preparation of 4-methyl-2'-cyanobiphenyl of formula: ##STR1## wherein a benzonitrile halide of general formula: ##STR2## in which Hal represents a halogen atom, is reacted, in the presence of a manganese salt, with an organometallic derivative of general formula: ##STR3## in which X represents a halogen atom, and the complex obtained is then hydrolysed, which provides the desired compound.
Claims8
A process for the preparation of 4-methyl-2'-cyano biphenyl of formula:
- ##STR7## wherein a benzonitrile halide of general formula:
- ##STR8## in which Hal represents halogen, is reacted, in the presence of a manganous salt, with an organometallic compound of general formula:
- ##STR9## in which X represents halogen and the complex obtained is then hydrolysed, which provides the desired compound.
Dependencies are inferred from the claim text.