Stable parenteral solution of 2-phenyl-1.2-benzisoselenazol-3(2H)-one and process for producing the same
AssigneeA. Nattermann & Cie GmbH
InventorsJoerg Hager, Andrea M. Huether, Joachim Roeding
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Abstract
The present invention is related to new parenteral preparations of 2-phenyl-1.2-benzisoselenazol-3(2H)-one (Ebselen) comprising additionally one or several phospholipids and, possibly, one or several auxiliary agents. The invention is further related to a process for producing such solutions and their use in the preparation of drug preparations ob Ebselen.
Claims4
Stable injectable solution of 2-phenyl-1.2-benzisoselenazol-3(2H)-one, characterized in that they contain a water-soluble combination of 2-phenyl-1.2-benzisoselenazol-3(2H)-one with one or several phospholipids, the weight proportion of 2-phenyl-1.2-benzisoselenazol-3(2H)-one and the phospholipid or phospholipids in the solution being between 1:2500 to 1:15.
Dependencies are inferred from the claim text.