Multiwell stat test
AssigneeSangStat Medical Corporation
InventorsPhilippe Pouletty, Beth Atwood, David Rammler
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Abstract
An apparatus is provided for the detection and semi-quantitative measurement of analytes. The assay results are visualized by the formation on a filter of a colored annular or circular spot, the diameter of the spot being related to the concentration of the analyte of interest. The filter on which the assay results are visualized is divided into multiple regions by strips of non-porous tape crossing the filter surface. The invention also includes a component for diluting sample to a suitable concentration for analysis, and dispensing the diluted sample onto the test filter.
Claims10
A diagnostic device for measuring an analyte which is a member of a specific binding pair, where a label is employed for said measuring which label provides for a visual detectable signal, said device comprising:
- a housing comprising an upper reservoir portion and a lower casing portion for holding at least one layer;
- in said casing in the direction of flow:
- a porous reactive filter as the floor of said reservoir component comprising a measurement circle of a member of a specific binding pair immobilized to said filter and defining a concentration gradient comprising an inner circle at an elevated concentration and an outer contiguous circle at a substantially lower concentration;
- and
- fluid receiving means for receiving fluid from said porous reactive filter.
A diagnostic device for measuring an analyte comprising a porous reactive filter comprising at least one region and in at least one of said regions, a measurement circle of a member of a specific binding pair immobilized to said filter and defining a concentration gradient comprising an inner circle at an elevated concentration and an outer contiguous circle at a substantially lower concentration.
Dependencies are inferred from the claim text.