Expression system for RSV glycoprotein F and G
AssigneeThe Upjohn Company
InventorMichael W. Wathen
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Abstract
This invention encompasses DNA compositions encoding novel chimeric glycoproteins which are useful for preparing virus specific immune responses against human respiratory syncytial virus. The DNA compositions include structural genes coding for the glycoproteins and expression and replication plasmids containing the structural genes. Host cells transformed with the above DNA compositions, vaccines made from the glycoproteins and methods for protecting humans by inoculation with said vaccines are also part of this invention.
Claims9
An expression system comprising a host selected from the group consisting of bacteria cells, yeast cells, mammalian cells and insect cells containing a gene for expressing a polypeptide having an immunogenic fragment from both human respiratory syncytial virus glycoprotein F and human respiratory syncytial virus glycoprotein G.
Dependencies are inferred from the claim text.