Back to results
US 5,288,616 AGranted
Process for producing proteins using silkworms infected with recombinant virus
AssigneeKatakura Industries Co., Ltd.
InventorsHironobu Okazaki, Toshimichi Kanaya, Sayuri Nishimura
Life of this patent
Estimating the term…
Abstract
An economic protein can be produced by using silkworms. The silkworms are chilled, warmed, and then orally infected with a virus in which a gene coding the target protein has been inserted. The silkworms so infected are then raised, followed by the collection of the target protein from the silkworms.
Claims3
A process for producing a protein using silkworms, which comprises:
- chilling the silkworms to a temperature of from 0 to 10.degree. C.;
- allowing the chilled silkworms to warm to about 25.degree. C. to awaken the silkworms from a temporary diapause caused by said chilling step;
- orally administering to said silkworms a feed containing a recombinant Bm nuclear polyhedrosis virus in an amount effective to infect the silkworms into which has been inserted a gene encoding said protein;
- raising said silkworms;
- and isolating said protein from said silkworms.
2 more elements
Dependencies are inferred from the claim text.